Article
Genetic susceptibility or resistance to autoimmune encephalomyelitis in MHC congenic mice is associated with differential production of pro- and anti-inflammatory cytokines.
International immunology - 1 Sept 1999
Maron R, Hancock W W, Slavin A, Hattori M, Kuchroo V, Weiner H L
Abstract excerpt
Experimental allergic encephalomyelitis (EAE) is a T(h)1-type cell-mediated autoimmune disease induced by immunization with myelin proteins and mediated by CD4(+) T cells. Although susceptibility to EAE is dependent largely on MHC background, the B10.S strain is resistant to induction of EAE desp...
Read the complete abstract on PubMedTopics
Share this publication in a Topic to start or enrich a Post.