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Article

Defective trophoblast function in mice with a targeted mutation of Ets2.

Genes & development - 1 May 1998

Yamamoto H, Flannery M L, Kupriyanov S, Pearce J, McKercher S R, Henkel G W, Maki R A, Werb Z, Oshima R G

Abstract excerpt

Members of the Ets family of transcription factors mediate transcriptional responses of multiple signaling pathways in diverse cell types and organisms. Targeted deletion of the conserved DNA binding domain of the Ets2 transcription factor results in the retardation and death of homozygous mouse embryos before 8.5 days of embryonic development. Defects in extraembryonic tissue gene expression and function include...

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Identifiers

PMID: 9573048
DOI: 10.1101/gad.12.9.1315
PMCID: PMC316781

Genes

EGF
FGF1
FGF2

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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