Article
BIMAAPC3, a component of the Aspergillus anaphase promoting complex/cyclosome, is required for a G2 checkpoint blocking entry into mitosis in the absence of NIMA function.
Journal of cell science - 1 May 1998
Lies C M, Cheng J, James S W, Morris N R, O'Connell M J, Mirabito P M
Abstract excerpt
Temperature sensitive (ts) nimA mutants of Aspergillus nidulans arrest at a unique point in G2 which is post activation of CDC2. Here we show that this G2 arrest is due to loss of nimA function and that it is dependent on BIMAAPC3, a component of the anaphase promoting complex/cyclosome (APC/C)....
Topics
- Alleles
- Anaphase
- Anaphase-Promoting Complex-Cyclosome
- Aspergillus nidulans
- CDC2 Protein Kinase
- Cell Cycle Proteins
- Cell Division
- Culture Media
- Cyclin B
- Ethanol
- Fungal Proteins
- G2 Phase
- Gene Expression Regulation, Enzymologic
- Gene Expression Regulation, Fungal