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Article

bimA encodes a member of the tetratricopeptide repeat family of proteins and is required for the completion of mitosis in Aspergillus nidulans.

Journal of cell science - 1 Aug 1991

O'Donnell K L, Osmani A H, Osmani S A, Morris N R

Abstract excerpt

The recessive, temperature-sensitive bimA1 mutation of Aspergillus nidulans blocks nuclei in metaphase at restrictive temperature. To determine whether the bimA product is essential, integrative transformation was used to create a mutation in the bimA gene. The mutation was maintained in a heterokaryon and the phenotype of spores produced by the heterokaryon was analyzed. Molecular disruption of the wild-type...

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Source

Identifiers

PMID: 1770001
DOI: 10.1242/jcs.99.4.711

Genes

TPR

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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bimA encodes a member of the tetratricopeptide repeat family of proteins and is required for the completion of mitosis in Aspergillus nidulans.PMID 1770001Read ↗

The bimB3 mutation of Aspergillus nidulans uncouples DNA replication from the completion of mitosis.Semantic proximity Read ↗

A negative regulator of mitosis in Aspergillus is a putative membrane-spanning protein.Semantic proximity Read ↗

Mutation of a gene that encodes a kinesin-like protein blocks nuclear division in A. nidulans.Semantic proximity Read ↗

Mutation in the bimD gene of Aspergillus nidulans confers a conditional mitotic block and sensitivity to DNA damaging agents.Semantic proximity Read ↗

A temperature-sensitive splicing mutation in the bimG gene of Aspergillus produces an N-terminal fragment which interferes with type 1 protein phosphatase function.Semantic proximity Read ↗

The Aspergillus nidulans bimE (blocked-in-mitosis) gene encodes multiple cell cycle functions involved in mitotic checkpoint control and mitosis.Semantic proximity Read ↗

Evidence for a NIMA-like mitotic pathway in vertebrate cells.Semantic proximity Read ↗

PINA is essential for growth and positively influences NIMA function in Aspergillus nidulans.Semantic proximity Read ↗

BIMAAPC3, a component of the Aspergillus anaphase promoting complex/cyclosome, is required for a G2 checkpoint blocking entry into mitosis in the absence of NIMA function.Semantic proximity Read ↗

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Mitotic regulation in Aspergillus nidulans.Semantic proximity Read ↗

Dynamic distribution of BIMG(PP1) in living hyphae of Aspergillus indicates a novel role in septum formation.Semantic proximity Read ↗

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