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Article

The NIMA protein kinase is hyperphosphorylated and activated downstream of p34cdc2/cyclin B: coordination of two mitosis promoting kinases.

The EMBO journal - 1 Mar 1995

Ye X S, Xu G, Pu R T, Fincher R R, McGuire S L, Osmani A H, Osmani S A

Abstract excerpt

Initiation of mitosis in Aspergillus nidulans requires activation of two protein kinases, p34cdc2/cyclin B and NIMA. Forced expression of NIMA, even when p34cdc2 was inactivated, promoted chromatin condensation. NIMA may therefore directly cause mitotic chromosome condensation. However, the mitosis-promoting function of NIMA is normally under control of p34cdc2/cyclin B as the active G2 form of NIMA is...

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Methodology Data sources Editorial policy Privacy Delete account & data About Contact Helena Bioinformatics

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Identifiers

PMID: 7889944
DOI: 10.1002/j.1460-2075.1995.tb07079.x
PMCID: PMC398170

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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The NIMA protein kinase is hyperphosphorylated and activated downstream of p34cdc2/cyclin B: coordination of two mitosis promoting kinases.PMID 7889944Read ↗

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Expression of the noncatalytic domain of the NIMA kinase causes a G2 arrest in Aspergillus nidulans.Semantic proximity Read ↗

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