Article
Expression of the noncatalytic domain of the NIMA kinase causes a G2 arrest in Aspergillus nidulans.
The EMBO journal - 1 May 1994
Lu K P, Means A R
Abstract excerpt
Temperature-sensitive mutation of the nimA gene of Aspergillus nidulans causes a reversible G2 arrest, whereas overexpression of nimA causes premature entry into mitosis from which the cells cannot exit. The nimA gene encodes a Ser/Thr-specific protein kinase (NIMA) which contains an extended COO...
Topics
- Alcohol Dehydrogenase
- Amino Acid Sequence
- Aspergillus nidulans
- Base Sequence
- Binding, Competitive
- Catalysis
- Cell Cycle Proteins
- DNA, Fungal
- G2 Phase
- Genetic Complementation Test
- Molecular Sequence Data
- Mutation
- NIMA-Related Kinase 1
- NIMA-Related Kinases
- Phenotype
- Promoter Regions, Genetic
- Protamine Kinase
- Protein Serine-Threonine Kinases