Article
Regulation of the anaphase-promoting complex/cyclosome by bimAAPC3 and proteolysis of NIMA.
Molecular biology of the cell - 1 Nov 1998
Ye X S, Fincher R R, Tang A, Osmani A H, Osmani S A
Abstract excerpt
Surprisingly, although highly temperature-sensitive, the bimA1(APC3) anaphase-promoting complex/cyclosome (APC/C) mutation does not cause arrest of mitotic exit. Instead, rapid inactivation of bimA1(APC3) is shown to promote repeating oscillations of chromosome condensation and decondensation, ac...
Topics
- Anaphase
- Anaphase-Promoting Complex-Cyclosome
- Aspergillus nidulans
- CDC2 Protein Kinase
- Cell Cycle
- Cell Cycle Proteins
- Cyclins
- Endopeptidases
- Fungal Proteins
- G2 Phase
- Ligases
- Mitosis
- Mutagenesis
- Mutation
- NIMA-Related Kinase 1
- NIMA-Related Kinases
- Nuclear Proteins
- Protein Serine-Threonine Kinases