Article
The NIMA kinase: a mitotic regulator in Aspergillus nidulans and vertebrate cells.
Progress in cell cycle research - 1 Jan 1995
Lu K P, Hunter T
Abstract excerpt
CDC2 has been shown to regulate entry into mitosis in eukaryotic cells. However, in Aspergillus nidulans, activation of CDC2 itself is not sufficient to trigger mitosis if another mitotic protein kinase, NIMA, is not activated. Superficially, NIMA and CDC2 have analogous functions and are regulated in a similar manner. NIMA activity is tightly regulated during the cell cycle. Overexpression of NIMA induces...
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