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Article

The NIMA kinase: a mitotic regulator in Aspergillus nidulans and vertebrate cells.

Progress in cell cycle research - 1 Jan 1995

Lu K P, Hunter T

Abstract excerpt

CDC2 has been shown to regulate entry into mitosis in eukaryotic cells. However, in Aspergillus nidulans, activation of CDC2 itself is not sufficient to trigger mitosis if another mitotic protein kinase, NIMA, is not activated. Superficially, NIMA and CDC2 have analogous functions and are regulat...

Topics

Amino Acid Sequence
Animals
Aspergillus nidulans
Cell Cycle
Cell Cycle Proteins
G2 Phase
HeLa Cells
Humans
Mitosis
Molecular Sequence Data
Mutation
NIMA-Related Kinase 1
NIMA-Related Kinases

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Phylogeny

Protein Serine-Threonine Kinases

Substrate Specificity

Xenopus

Source

Identifiers

PMID: 9552363
DOI: 10.1007/978-1-4615-1809-9_15

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 30 Aug 2026. Prepared record publication-9552363-2026-08-30.1. Manifest publication-graph-cohort-2026-08-30.1.

Source receipt: PubMed via Helena Literature Corpus, retrieved 30 Aug 2026.

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The NIMA kinase: a mitotic regulator in Aspergillus nidulans and vertebrate cells.PMID 9552363Read ↗

Evidence for a NIMA-like mitotic pathway in vertebrate cells.Semantic proximity Read ↗

Parallel activation of the NIMA and p34cdc2 cell cycle-regulated protein kinases is required to initiate mitosis in A. nidulans.Semantic proximity Read ↗

The NIMA protein kinase is hyperphosphorylated and activated downstream of p34cdc2/cyclin B: coordination of two mitosis promoting kinases.Semantic proximity Read ↗

Cell cycle regulation by the NEK family of protein kinasesSemantic proximity Read ↗

Role of the cell-cycle-regulated NIMA protein kinase during G2 and mitosis: evidence for two pathways of mitotic regulation.Semantic proximity Read ↗

Expression of the noncatalytic domain of the NIMA kinase causes a G2 arrest in Aspergillus nidulans.Semantic proximity Read ↗

Activation of the nimA protein kinase plays a unique role during mitosis that cannot be bypassed by absence of the bimE checkpoint.Semantic proximity Read ↗

A NIMA homologue promotes chromatin condensation in fission yeast.Semantic proximity Read ↗

PINA is essential for growth and positively influences NIMA function in Aspergillus nidulans.Semantic proximity Read ↗

A single p34cdc2 protein kinase (encoded by nimXcdc2) is required at G1 and G2 in Aspergillus nidulans.Semantic proximity Read ↗

Potential link between the NIMA mitotic kinase and nuclear membrane fission during mitotic exit in Aspergillus nidulans.Semantic proximity Read ↗

Essential roles for calcium and calmodulin in G2/M progression in Aspergillus nidulans.Semantic proximity Read ↗

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