Article
Mad1p, a phosphoprotein component of the spindle assembly checkpoint in budding yeast.
The Journal of cell biology - 1 Nov 1995
Hardwick K G, Murray A W
Abstract excerpt
The spindle assembly checkpoint prevents cells from initiating anaphase until the spindle has been fully assembled. We previously isolated mitotic arrest deficient (mad) mutants that inactivate this checkpoint and thus increase the sensitivity of cells to benomyl, a drug that interferes with mito...
Topics
- Amino Acid Sequence
- Base Sequence
- Carrier Proteins
- Cell Cycle Proteins
- Cell Nucleus
- Fungal Proteins
- Molecular Sequence Data
- Mutation
- Nuclear Proteins
- Phosphoproteins
- Phosphorylation
- Repressor Proteins
- Spindle Apparatus
- Yeasts