Article
High-resolution characterization of cytokine-producing alloreactivity in naive and allograft-primed mice.
Transplantation - 15 Apr 1998
Matesic D, Lehmann P V, Heeger P S
Abstract excerpt
BACKGROUND: Whether alloreactive T cells in a naive host derive from naive or memory T cells remains unclear. It is also unclear whether graft rejection alters the phenotype of these T cells. Proliferation assays and cytokine enzyme-linked immunosorbent assays performed on culture supernatants do not differentiate primary T-cell alloreactivity from recall responses in allograft-primed mice, suggesting that these...
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