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Article

Brief antigenic stimulation generates effector CD8 T cells with low cytotoxic activity and high IL-2 production.

Journal of immunology (Baltimore, Md. : 1950) - 1 Apr 2008

Usharauli David, Kamala Tirumalai

Abstract excerpt

It is currently believed that a brief antigenic stimulation is sufficient to induce CD8 T cells to complete their differentiation program, become effector T cells, and subsequently generate memory. Because this concept was derived from studies in which only a single effector function was analyzed (either IFN-gamma production or target cell lysis), we wondered whether monitoring for multiple effector functions...

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Source

Identifiers

PMID: 18354172
DOI: 10.4049/jimmunol.180.7.4507

Genes

TNF

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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