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Article

Chromosome 14 contains determinants that regulate susceptibility to Theiler's virus-induced demyelination in the mouse.

Genetics - 1 Apr 1998

Bureau J F, Drescher K M, Pease L R, Vikoren T, Delcroix M, Zoecklein L, Brahic M, Rodriguez M

Abstract excerpt

Theiler's murine encephalomyelitis virus causes a chronic demyelinating disease in susceptible strains of mice that is similar to human multiple sclerosis. Several nonmajor histocompatibility complex-linked genes have been implicated as determinants of susceptibility or resistance to either demyelination or virus persistence. In this study, we used linkage analysis of major histocompatibility complex identical...

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Source

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Identifiers

PMID: 9560407
DOI: 10.1093/genetics/148.4.1941
PMCID: PMC1460094

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Source receipt: pubmed, retrieved 7 Sept 2026.

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