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Article

Identification of murine loci associated with susceptibility to chronic experimental autoimmune encephalomyelitis.

Nature genetics - 1 Jul 1995

Sundvall M, Jirholt J, Yang H T, Jansson L, Engström A, Pettersson U, Holmdahl R

Abstract excerpt

B10.RIII mice develop chronic and relapsing experimental autoimmune encephalomyelitis (EAE) after immunization with the myelin basic protein (MBP) peptide 89-101. The disease is associated with the major histocompatibility complex (MHC) (eae1). We have now investigated the importance of non-MHC regions for the EAE susceptibility in a cross between RIIIS/J and B10.RIII mice which share the MHC region but differ in...

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PMID: 7545492
DOI: 10.1038/ng0795-313

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MBP

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