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Article

Telomerase Activity in Candidate Stem Cells From Fetal Liver and Adult Bone Marrow

1 May 1998

Abstract excerpt

Telomerase is a ribonucleoprotein polymerase that synthesizes telomeric repeats onto the 3' ends of eukaryotic chromosomes. Activation of telomerase may prevent telomeric shortening and correlates with cell immortality in the germline and certain tumor cells. Candidate hematopoietic stem cells (HSC) from adult bone marrow express low levels of telomerase, which is upregulated with proliferation and/or...

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PMID: 9558381
DOI: 10.1182/blood.v91.9.3255

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Telomerase Activity in Candidate Stem Cells From Fetal Liver and Adult Bone MarrowPMID 9558381Read ↗

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The frequency of multipotent CD133(+)CD45RA(-)CD34(+) hematopoietic stem cells is not increased in fetal liver compared with adult stem cell sources.Semantic proximity Read ↗

In Vitro Expansion of Human Hepatocytes is Restricted by Telomere-Dependent Replicative AgingSemantic proximity Read ↗

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