Article
Phenotypic and functional analysis of human fetal liver hematopoietic stem cells in culture.
Stem cells and development - 1 Apr 2007
Rollini Pierre, Faes-Van't Hull Eveline, Kaiser Stefan, Kapp Ursula, Leyvraz Serge
Abstract excerpt
Steady-state hematopoiesis and hematopoietic transplantation rely on the unique potential of stem cells to undergo both self-renewal and multilineage differentiation. Fetal liver (FL) represents a promising alternative source of hematopoietic stem cells (HSCs), but limited by the total cell number obtained in a typical harvest. We reported that human FL nonobese diabetic/severe combined immunodeficient (NOD/SCID)...
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