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Article

Characterization of human hematopoietic cells with short-lived in vivo repopulating activity.

Annals of the New York Academy of Sciences - 1 Jun 2001

Eaves C, Glimm H, Eisterer W, Audet J, Maguer-Satta V, Piret J

Abstract excerpt

Recent studies with purified hematopoietic stem cells in vitro support a model of stem cell self-renewal control that involves distinct mechanisms regulating permissiveness to and execution of lineage restriction. Such a model predicts the existence of phenotypically separable populations of hematopoietic cells that are pluripotent and either capable or incapable of extensive self-renewal. Such populations have...

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PMID: 11458527
DOI: 10.1111/j.1749-6632.2001.tb03575.x

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