Article
Characterization of human hematopoietic cells with short-lived in vivo repopulating activity.
Annals of the New York Academy of Sciences - 1 Jun 2001
Eaves C, Glimm H, Eisterer W, Audet J, Maguer-Satta V, Piret J
Abstract excerpt
Recent studies with purified hematopoietic stem cells in vitro support a model of stem cell self-renewal control that involves distinct mechanisms regulating permissiveness to and execution of lineage restriction. Such a model predicts the existence of phenotypically separable populations of hematopoietic cells that are pluripotent and either capable or incapable of extensive self-renewal. Such populations have...
Topics
- Animals
- Cell Count
- Cell Differentiation
- Cell Division
- Cell Lineage
- Cells, Cultured
- Colony-Forming Units Assay
- Cytokines
- Hematopoiesis
- Hematopoietic Stem Cell Transplantation
- Hematopoietic Stem Cells
- Humans
- Mice
- Mice, Inbred NOD