Article
Polymorphisms in the human cytochrome P-450 1A1 gene (CYP1A1) as a factor for developing acne.
Dermatology (Basel, Switzerland) - 1 Jan 1998
Paraskevaidis A, Drakoulis N, Roots I, Orfanos C E, Zouboulis C C
Abstract excerpt
Cytochromes P-450 are a supergene family of enzymes involved in the metabolism of a wide range of endogenous and foreign compounds. The existing genetic variations of the distinct isozymes lead to interindividually different metabolic capacity. Since vitamin A, endogenous retinoids and their natu...
Topics
- Acne Vulgaris
- Alleles
- Cytochrome P-450 CYP1A1
- Humans
- Mutation
- Polymerase Chain Reaction
- Polymorphism, Genetic
- Polymorphism, Restriction Fragment Length
