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Article

Allelic variants of drug metabolizing enzymes as risk factors in psoriasis.

The Journal of investigative dermatology - 1 May 2003

Richter-Hintz Dagmar, Their Ricarda, Steinwachs Swantje, Kronenberg Sven, Fritsche Ellen, Sachs Bernd, Wulferink Marty, Tonn Torsten, Esser Charlotte

Abstract excerpt

The onset or exacerbation of psoriasis, a T-cell-dependent skin disease with autoimmune features, can be triggered by drugs such as antimalarials and beta-blockers. Xenobiotics may also play a role in idiopathic psoriasis. It has been hypothesized that different metabolic efficiencies caused by variant alleles of xenobiotic metabolizing enzymes could lead to the accumulation of xenobiotics or their reactive...

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Share to Aryl Hydrocarbon Hydroxylases
Share to Cytochrome P-450 CYP1A1

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Share to Polymorphism, Restriction Fragment Length

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Source

Identifiers

PMID: 12713578
DOI: 10.1046/j.1523-1747.2003.12124.x

Genes

GSTM1
GSTT1

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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