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Article

Transformation of Rickettsia prowazekii to rifampin resistance.

Journal of bacteriology - 1 Apr 1998

Rachek L I, Tucker A M, Winkler H H, Wood D O

Abstract excerpt

Rickettsia prowazekii, the causative agent of epidemic typhus, is an obligate intracellular parasitic bacterium that grows directly within the cytoplasm of the eucaryotic host cell. The absence of techniques for genetic manipulation hampers the study of this organism's unique biology and pathogenic mechanisms. To establish the feasibility of genetic manipulation in this organism, we identified a specific mutation...

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Identifiers

PMID: 9555894
DOI: 10.1128/JB.180.8.2118-2124.1998
PMCID: PMC107138

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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