Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Rrp2, a prokaryotic enhancer-like binding protein, is essential for viability of Borrelia burgdorferi.

Journal of bacteriology - 1 Jul 2012

Groshong Ashley M, Gibbons Nora E, Yang X Frank, Blevins Jon S

Abstract excerpt

The Lyme disease spirochete, Borrelia burgdorferi, exists in two diverse niches (i.e., an arthropod tick vector and mammalian host) during its enzootic life cycle. To effectively adapt to these unique environments, the bacterium alters the expression of numerous genes, including several major outer surface (lipo)proteins that are required for infection and transmission. An enhancer-binding protein (EBP), known as...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Bacterial Proteins
Share to Borrelia burgdorferi
Share to DNA-Binding Proteins

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Gene Expression Regulation, Bacterial

Share to Genes, Essential

Share to Microbial Viability

Share to RNA Polymerase Sigma 54

Share to Sigma Factor

Source

Open in PubMed Open full text

Identifiers

PMID: 22544267
DOI: 10.1128/JB.00253-12
PMCID: PMC3434732

Genes

EBP

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Rrp2, a prokaryotic enhancer-like binding protein, is essential for viability of Borrelia burgdorferi.PMID 22544267Read ↗

The putative Walker A and Walker B motifs of Rrp2 are required for the growth of Borrelia burgdorferi.Semantic proximity Read ↗

The RpoS Gatekeeper in Borrelia burgdorferi: An Invariant Regulatory Scheme That Promotes Spirochete Persistence in Reservoir Hosts and Niche DiversitySemantic proximity Read ↗

Activation of the RpoN-RpoS regulatory pathway during the enzootic life cycle of Borrelia burgdorferiSemantic proximity Read ↗

Who is the BosR around here anyway?Semantic proximity Read ↗

Expression of <i>Borrelia burgdorferi</i> OspC and DbpA is controlled by a RpoN–RpoS regulatory pathwaySemantic proximity Read ↗

Coupled induction of prophage and virulence factors during tick transmission of the Lyme disease spirocheteSemantic proximity Read ↗

Positive feedback regulation between RpoS and BosR in the Lyme disease pathogenSemantic proximity Read ↗

Regulators of Expression of the Oligopeptide Permease A Proteins of Borrelia burgdorferiSemantic proximity Read ↗

Global Repression of Host-Associated Genes of the Lyme Disease Spirochete through Post-Transcriptional Modulation of the Alternative Sigma Factor RpoSSemantic proximity Read ↗

Positive feedback regulation between RpoS and BosR in the Lyme disease pathogenSemantic proximity Read ↗

Transcriptomic insights on the virulence-controlling CsrA, BadR, RpoN, and RpoS regulatory networks in the Lyme disease spirochete.Semantic proximity Read ↗

CsrA Modulates Levels of Lipoproteins and Key Regulators of Gene Expression Critical for Pathogenic Mechanisms of Borrelia burgdorferiSemantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.