Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

In Vivo Regulation of the IκB Homologue cactus during the Immune Response of Drosophila

1 Apr 1998

Abstract excerpt

The dorsoventral regulatory gene pathway (spätzle/Toll/cactus) controls the expression of several antimicrobial genes during the immune response of Drosophila. This regulatory cascade shows striking similarities with the cytokine-induced activation cascade of NF-kappaB during the inflammatory response in mammals. Here, we have studied the regulation of the IkappaB homologue Cactus in the fat body during the...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Invertebrate Immune Response Mechanisms
Share to Mosquito-borne diseases and control
Share to Neurobiology and Insect Physiology Research

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Source

Identifiers

PMID: 9553105
DOI: 10.1074/jbc.273.17.10463

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

In Vivo Regulation of the IκB Homologue cactus during the Immune Response of DrosophilaPMID 9553105Read ↗

The dorsoventral regulatory gene cassette spätzle/Toll/cactus controls the potent antifungal response in Drosophila adults.Semantic proximity Read ↗

A Toll-dependent Bre1/Rad6-cact feedback loop in controlling host innate immune responseSemantic proximity Read ↗

Calpain A modulates Toll responses by limited Cactus/IκB proteolysis.Semantic proximity Read ↗

The Ca2+-dependent protease Calpain A regulates Cactus/I kappaB levels during Drosophila development in response to maternal Dpp signals.Semantic proximity Read ↗

A novel function for the IκB inhibitor Cactus in promoting Dorsal nuclear localization and activity in the Drosophila embryo.Semantic proximity Read ↗

Regulated nuclear import of Rel proteins in the Drosophila immune response.Semantic proximity Read ↗

A gradient of cytoplasmic Cactus degradation establishes the nuclear localization gradient of the dorsal morphogen in Drosophila.Semantic proximity Read ↗

Identification, Characterization, and Function Analysis of the Cactus Gene from Litopenaeus vannameiSemantic proximity Read ↗

Toll-8/Tollo negatively regulates antimicrobial response in the Drosophila respiratory epithelium.Semantic proximity Read ↗

Drosophila Rel proteins are central regulators of a robust, multi-organ immune network.Semantic proximity Read ↗

Cooperative control of Drosophila immune responses by the JNK and NF-kappaB signaling pathways.Semantic proximity Read ↗

Cactus protein degradation mediates Drosophila dorsal-ventral signaling.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.