A Toll-dependent Bre1/Rad6-cact feedback loop in controlling host innate immune response

Abstract excerpt

The Toll signaling pathway was initially identified for its involvement in the control of early embryogenesis. It was later shown to be also part of a major innate immune pathway controlling the expression of anti-microbial peptides in many eukaryotes including humans; cactus, the essential negative regulator of this pathway in flies, was found to be induced in parallel to the Toll-dependent activation process...

Topics

Share this publication in a Topic to start or enrich a Post.

• Share to Insect symbiosis and bacterial influences
• Share to Invertebrate Immune Response Mechanisms
• Share to Mosquito-borne diseases and control