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Article

Drosophila Rel proteins are central regulators of a robust, multi-organ immune network.

Journal of cell science - 15 Feb 2010

Matova Nina, Anderson Kathryn V

Abstract excerpt

Survival of all animals depends on effective protection against infection. In Drosophila, opportunistic infection kills larvae if they lack the Rel/NF-kappaB proteins Dorsal and Dif. We have used tissue-specific expression of Dif and Dorsal to reveal that these Rel proteins act in three different tissues to defend larvae from infection. Dif and Dorsal act in circulating blood cells, where they are required...

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Identifiers

PMID: 20145002
DOI: 10.1242/jcs.060731
PMCID: PMC2818199

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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