Article
Cooperative control of Drosophila immune responses by the JNK and NF-kappaB signaling pathways.
The EMBO journal - 12 Jul 2006
Delaney Joseph R, Stöven Svenja, Uvell Hanna, Anderson Kathryn V, Engström Ylva, Mlodzik Marek
Abstract excerpt
Jun N-terminal kinase (JNK) signaling is a highly conserved pathway that controls both cytoskeletal remodeling and transcriptional regulation in response to a wide variety of signals. Despite the importance of JNK in the mammalian immune response, and various suggestions of its importance in Drosophila immunity, the actual contribution of JNK signaling in the Drosophila immune response has been unclear....
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