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Article

Regulated nuclear import of Rel proteins in the Drosophila immune response.

Nature - 5 Mar 1998

Wu L P, Anderson K V

Abstract excerpt

The Drosophila immune response uses many of the same components as the mammalian innate immune response, including signalling pathways that activate transcription factors of the Rel/NK-kappaB family. In response to infection, two Rel proteins, Dif and Dorsal, translocate from the cytoplasm to the nuclei of larval fat-body cells. The Toll signalling pathway, which controls dorsal-ventral patterning during...

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PMID: 9510254
DOI: 10.1038/32195

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