Potential link between the NIMA mitotic kinase and nuclear membrane fission during mitotic exit in Aspergillus nidulans.

doi:10.1128/EC.3.6.1433-1444.2004

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Article

Potential link between the NIMA mitotic kinase and nuclear membrane fission during mitotic exit in Aspergillus nidulans.

Eukaryotic cell - 1 Dec 2004

Davies Jonathan R, Osmani Aysha H, De Souza Colin P C, Bachewich Catherine, Osmani Stephen A

Abstract excerpt

We have isolated TINC as a NIMA-interacting protein by using the yeast two-hybrid system and have confirmed that TINC interacts with NIMA in Aspergillus nidulans. The TINC-NIMA interaction is stabilized in the absence of phosphatase inhibitors and in the presence of kinase-inactive NIMA, suggesting that the interaction is enhanced when NIMA is not fully activated. TINC is a cytoplasmic protein. TINC homologues...

Topics

Alleles
Aspergillus nidulans
Cell Cycle Proteins
Cell Nucleus
Cloning, Molecular
Cytoplasm
DNA
DNA, Complementary
Enzyme Inhibitors
Gene Deletion
Green Fluorescent Proteins

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Microscopy, Fluorescence

Mitosis

NIMA-Related Kinase 1

Nuclear Envelope

Phenotype

Phylogeny

Protein Serine-Threonine Kinases

Source

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Identifiers

PMID: 15590818
DOI: 10.1128/EC.3.6.1433-1444.2004
PMCID: PMC539031

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