Article
A genome-wide screen for susceptibility loci in ankylosing spondylitis.
Arthritis and rheumatism - 1 Apr 1998
Brown M A, Pile K D, Kennedy L G, Campbell D, Andrew L, March R, Shatford J L, Weeks D E, Calin A, Wordsworth B P
Abstract excerpt
OBJECTIVE: To localize the regions containing genes that determine susceptibility to ankylosing spondylitis (AS). METHODS: One hundred five white British families with 121 affected sibling pairs with AS were recruited, largely from the Royal National Hospital for Rheumatic Diseases AS database. A genome-wide linkage screen was undertaken using 254 highly polymorphic microsatellite markers from the Medical...
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