Article
Genome-wide association study of ankylosing spondylitis identifies non-MHC susceptibility loci.
Nature genetics - 1 Feb 2010
Reveille John D, Sims Anne-Marie, Danoy Patrick, Evans David M, Leo Paul, Pointon Jennifer J, Jin Rui, Zhou Xiaodong, Bradbury Linda A, Appleton Louise H, Davis John C, Diekman Laura, Doan Tracey, Dowling Alison, Duan Ran, Duncan Emma L, Farrar Claire, Hadler Johanna, Harvey David, Karaderi Tugce, Mogg Rebecca, Pomeroy Emma, Pryce Karena, Taylor Jacqueline, Savage Laurie, Deloukas Panos, Kumanduri Vasudev, Peltonen Leena, Ring Sue M, Whittaker Pamela, Glazov Evgeny, Thomas Gethin P, Maksymowych Walter P, Inman Robert D, Ward Michael M, Stone Millicent A, Weisman Michael H, Wordsworth B Paul, Brown Matthew A
Abstract excerpt
To identify susceptibility loci for ankylosing spondylitis, we undertook a genome-wide association study in 2,053 unrelated ankylosing spondylitis cases among people of European descent and 5,140 ethnically matched controls, with replication in an independent cohort of 898 ankylosing spondylitis cases and 1,518 controls. Cases were genotyped with Illumina HumHap370 genotyping chips. In addition to strong...
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