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Article

Analysis of tumor suppressor gene p53 in chicken lymphoblastoid tumor cell lines and field tumors.

The Journal of veterinary medical science - 1 Aug 1998

Takagi M, Ohashi K, Morimura T, Sugimoto C, Onuma M

Abstract excerpt

To determine whether there is any abnormalities of the p53 gene in chicken lymphoblastoid tumor cell lines derived from Marek's disease (MD), lymphoid leukosis, reticuloendotheliosis, and field tumors, some portions of p53 cDNA corresponding to core and C-terminal domains (nucleotide positions 277-1104 in the p53 open reading frame (ORF)) were sequenced. Several mutations were identified in both cell lines and...

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PMID: 9764405
DOI: 10.1292/jvms.60.923

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