Article
Genetic analysis of the pX region of bovine leukemia virus genotype 1 in Holstein Friesian cattle with different stages of infection.
Archives of virology - 1 Jan 2022
Montero Machuca Neli, Tórtora Pérez Jorge Luis, González Méndez Ana Silvia, García-Camacho Angélica Lucia, Marín Flamand Ernesto, Ramírez Álvarez Hugo
Abstract excerpt
The pX genetic region of bovine leukemia virus (BLV) includes four genes with overlapping reading frames that code for the Tax, Rex, R3, and G4 proteins. These proteins are involved in the regulation of transcriptional and post-transcriptional viral expression, as well as having oncogenic potential. Our goal was to investigate the pathogenicity of the pX region of BLV genotype 1 in terms of lymphocytosis,...
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