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Mutations in the tumor suppressor gene p53 in cattle are associated with enzootic bovine leukosis.

Veterinary microbiology - 1 Dec 2021

Konishi Misako, Kameyama Ken-Ichiro, Yamamoto Takehisa

Abstract excerpt

Enzootic bovine leukosis (EBL) is a B-cell lymphoma caused by the bovine leukemia virus (BLV). Although an association between EBL and mutations in the bovine tumor suppressor gene TP53 (bTP53) has been suggested, the substantive incidence rate of bTP53 mutations in EBL cattle is still unclear. In this study, we investigated the complete sequence (exons 2-11) of bTP53 in tissue and peripheral blood leukocyte...

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Identifiers

PMID: 34781193
DOI: 10.1016/j.vetmic.2021.109269

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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