Article
Identification of GCD14 and GCD15, novel genes required for translational repression of GCN4 mRNA in Saccharomyces cerevisiae.
Genetics - 1 Mar 1998
Cuesta R, Hinnebusch A G, Tamame M
Abstract excerpt
In Saccharomyces cerevisiae, expression of the transcriptional activator GCN4 increases at the translational level in response to starvation for an amino acid. The products of multiple GCD genes are required for efficient repression of GCN4 mRNA translation under nonstarvation conditions. The maj...
Topics
- Alcohol Oxidoreductases
- Aminohydrolases
- Cloning, Molecular
- DNA-Binding Proteins
- Epistasis, Genetic
- Eukaryotic Initiation Factor-2
- Eukaryotic Initiation Factor-2B
- Fungal Proteins
- Gene Deletion
- Gene Expression Regulation, Fungal
- Genes, Dominant
- Genes, Fungal
- Genes, Recessive
- Genes, Regulator
- Genetic Complementation Test
- Meiosis
- Mutagenesis
- Phenotype