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Article

Defect in the GTPase activating protein (GAP) function of eIF5 causes repression of GCN4 translation.

Biochemical and biophysical research communications - 13 May 2017

Antony A Charles, Alone Pankaj V

Abstract excerpt

In eukaryotes, the eIF5 protein plays an important role in translation start site selection by providing the GAP (GTPase activating protein) function. However, in yeast translation initiation fidelity defective eIF5G31R mutant causes preferential utilization of UUG as initiation codon and is termed as Suppressor of initiation codon (Sui-) phenotype due to its hyper GTPase activity. The eIF5G31R mutant dominantly...

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PMID: 28385532
DOI: 10.1016/j.bbrc.2017.04.002

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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Defect in the GTPase activating protein (GAP) function of eIF5 causes repression of GCN4 translation.PMID 28385532Read ↗

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