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Apolipoprotein E isoform-specific differences in outcome from focal ischemia in transgenic mice.

Journal of cerebral blood flow and metabolism : official journal of the International Society of Cerebral Blood Flow and Metabolism - 1 Apr 1998

Sheng H, Laskowitz D T, Bennett E, Schmechel D E, Bart R D, Saunders A M, Pearlstein R D, Roses A D, Warner D S

Abstract excerpt

Apolipoprotein E (apoE), a 34-KD glycosylated lipid-binding protein, is expressed as three common isoforms in humans (E2, E3, or E4). Clinical evidence suggests that the apoE genotype (APOE) may be a risk factor for poor outcome after acute central nervous system injury. This was examined further...

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Alleles
Genotype
Mice
Species Specificity
Blotting, Western

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Mice, Transgenic

Apolipoproteins E

Apolipoprotein E4

Source

Identifiers

PMID: 9538900
DOI: 10.1097/00004647-199804000-00003

Genes

APOE

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 31 Aug 2026. Prepared record publication-9538900-2026-08-31.1. Manifest publication-graph-cohort-2026-08-31.1.

Source receipt: PubMed via Helena Literature Corpus, retrieved 31 Aug 2026.

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