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Article

Marked regional differences of brain human apolipoprotein E expression in targeted replacement mice.

Neuroscience - 1 Jan 2004

Sullivan P M, Mace B E, Maeda N, Schmechel D E

Abstract excerpt

We used three human apolipoprotein (apo) E targeted replacement mouse lines, each expressing one of the three common human apoE isoforms to study the pattern of apoE expression in the central nervous system (CNS). Immunocytochemistry on brain sections from all three lines of targeted replacement mice, wild type mice, African green monkeys, and humans show a predominantly glial pattern of apoE expression. The...

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Identifiers

PMID: 15026113
DOI: 10.1016/j.neuroscience.2003.10.011

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

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