Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

[Current data on the role of APC protein in the origin of colorectal cancer].

Bulletin du cancer - 1 Nov 1997

Bonneton C, Larue L, Thiery J P

Abstract excerpt

The adenomatous polyposis coli (APC) gene has been found to be mutated during the development of sporadic colorectal cancers as well as in familial adenomatous polyposis (FAP). These conditions result from initially somatic and germ line mutations respectively. In both cases, the expressed protei...

Topics

Adenomatous Polyposis Coli
Animals
Cell Physiological Phenomena
Colonic Neoplasms
Cytoskeletal Proteins
Disease Models, Animal
Gene Expression Regulation
Genes, APC
Humans
Mutation
Rats
Rectal Neoplasms

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Trans-Activators

Tumor Cells, Cultured

beta Catenin

Source

Identifiers

PMID: 9536987

Genes

APC
FAP

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 30 Aug 2026. Prepared record publication-9536987-2026-08-30.1. Manifest publication-graph-cohort-2026-08-30.1.

Source receipt: PubMed via Helena Literature Corpus, retrieved 30 Aug 2026.

Community interpretation

Discuss the evidence

Ask a question, add context or challenge an interpretation. Community activity is separate from scientific evidence strength.

0

discussions

0

replies

Citations encouraged

Claims remain attributable.

No discussion yet

Be the first to add a careful, cited interpretation.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

[Current data on the role of APC protein in the origin of colorectal cancer].PMID 9536987Read ↗

A Common Role for Various Human Truncated Adenomatous Polyposis Coli Isoforms in the Control of Beta-Catenin Activity and Cell ProliferationSemantic proximity Read ↗

Multiple Roles of APC and its Therapeutic Implications in Colorectal Cancer.Semantic proximity Read ↗

[The APC gene].Semantic proximity Read ↗

[Familial adenomatous polyposis syndrome (FAP): pathogenesis and molecular mechanisms].Semantic proximity Read ↗

The ABC of APC.Semantic proximity Read ↗

The adenomatous polyposis coli (APC) tumour suppressor--genetics, function and disease.Semantic proximity Read ↗

[Role of Wnt signaling and APC protein in the etiology of colorectal cancer].Semantic proximity Read ↗

Biology of the adenomatous polyposis coli tumor suppressor.Semantic proximity Read ↗

The APC gene product in normal and tumor cells.Semantic proximity Read ↗

The adenomatous polyposis coli protein 30 years on.Semantic proximity Read ↗

C-Myc is a critical mediator of the phenotypes of Apc loss in the intestine.Semantic proximity Read ↗

Adenomatous polyposis coli (APC) plays multiple roles in the intestinal and colorectal epithelia.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.