[The APC gene].

Article

[The APC gene].

Nihon rinsho. Japanese journal of clinical medicine - 1 Apr 1996

Akiyama T

Abstract excerpt

The tumor suppressor gene APC is mutated in most cases of familial adenomatous polyposis (FAP) and sporadic colorectal tumors. The product of the APC gene is a 300 kDa protein present in the cytoplasm as a homodimer. Interestingly, the APC protein is known to interact with the adherence junction...

Topics

Adenomatous Polyposis Coli
Adenomatous Polyposis Coli Protein
Cell Adhesion
Cell Cycle
Cytoskeletal Proteins
Genes, APC
Humans
Mutation

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