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Article

The adenomatous polyposis coli protein 30 years on.

Seminars in cell & developmental biology - 1 Dec 2023

Abbott James, Näthke Inke S

Abstract excerpt

Mutations in the gene encoding the Adenomatous polyposis coli protein (APC) were discovered as driver mutations in colorectal cancers almost 30 years ago. Since then, the importance of APC in normal tissue homeostasis has been confirmed in a plethora of other (model) organisms spanning a large evolutionary space. APC is a multifunctional protein, with roles as a key scaffold protein in complexes involved in...

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Identifiers

PMID: 37095033
DOI: 10.1016/j.semcdb.2023.04.004

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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