Article
The role of Cdc42 in signal transduction and mating of the budding yeast Saccharomyces cerevisiae.
The Journal of biological chemistry - 10 Apr 1998
Oehlen L J, Cross F R
Abstract excerpt
The small G-protein Cdc42 functions in many eukaryotic signal transduction pathways. In the budding yeast Saccharomyces cerevisiae, cells with defective Cdc42 fail to induce mating-specific genes in response to mating factor and to adopt the proper morphology for conjugation. Here we show that the failure of mating factor-induced transcription is largely the indirect result of arrest at a specific cell cycle...
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