Article
APOE epsilon4 is not associated with Alzheimer's disease in elderly Nigerians.
Annals of neurology - 1 Jan 2006
Gureje Oye, Ogunniyi Adesola, Baiyewu Olusegun, Price Brandon, Unverzagt Frederick W, Evans Rebecca M, Smith-Gamble Valerie, Lane Kathleen A, Gao Sujuan, Hall Kathleen S, Hendrie Hugh C, Murrell Jill R
Abstract excerpt
Since 1992, research teams from Indiana University and the University of Ibadan have been collecting and comparing data from two diverse, elderly populations to identify risk factors for dementia and Alzheimer's disease. Apolipoprotein E (APOE) was genotyped in 2,245 Nigerian samples. Of these, 830 had a diagnosis: 459 were normal, and 140 had dementia including 123 diagnosed with Alzheimer's disease. In contrast...
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