Article
Suppressors of the temperature sensitivity of DNA polymerase alpha mutations in Saccharomyces cerevisiae.
Molecular & general genetics : MGG - 1 Feb 1998
Formosa T, Nittis T
Abstract excerpt
We have isolated two high copy, allele-specific suppressors of the temperature sensitivity of mutations in POL1, the gene that encodes the catalytic subunit of DNA polymerase alpha in the yeast Saccharomyces cerevisiae. Both genes, PSP1 and PSP2, also partially suppressed a mutation in POL3 which encodes DNA polymerase delta, and both also affected a mutation in CDC6, which acts in initiation of DNA replication....
Read the complete abstract on PubMedTopics
Share this publication in a Topic to start or enrich a Post.