Article
Suppressors of a Saccharomyces cerevisiae pkc1 mutation identify alleles of the phosphatase gene PTC1 and of a novel gene encoding a putative basic leucine zipper protein.
Genetics - 1 Dec 1995
Huang K N, Symington L S
Abstract excerpt
The PKC1 gene product, protein kinase C, regulates a mitogen-activated protein kinase (MAPK) cascade, which is implicated in cell wall metabolism. Previously, we identified the pkc1-4 allele in a screen for mutants with increased rates of recombination, indicating that PKC1 may also regulate DNA...
Topics
- Alleles
- Amino Acid Sequence
- Base Sequence
- Carboxy-Lyases
- Cloning, Molecular
- Fungal Proteins
- Genetic Complementation Test
- Leucine Zippers
- Molecular Sequence Data
- Mutation
- Phenotype
- Phosphoprotein Phosphatases