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Article

A suppressor of an RNA polymerase II mutation of Saccharomyces cerevisiae encodes a subunit common to RNA polymerases I, II, and III.

Molecular and cellular biology - 1 Dec 1990

Archambault J, Schappert K T, Friesen J D

Abstract excerpt

RNA polymerase II (RNAPII) is a complex multisubunit enzyme responsible for the synthesis of pre-mRNA in eucaryotes. The enzyme is made of two large subunits associated with at least eight smaller polypeptides, some of which are common to all three RNA polymerase species. We have initiated a genetic analysis of RNAPII by introducing mutations in RPO21, the gene encoding the largest subunit of RNAPII in...

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Identifiers

PMID: 2247052
DOI: 10.1128/mcb.10.12.6123-6131.1990
PMCID: PMC362887

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