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Article

Multiple mechanisms of suppression circumvent transcription defects in an RNA polymerase mutant.

Molecular and cellular biology - 1 Nov 2000

Tan Q, Li X, Sadhale P P, Miyao T, Woychik N A

Abstract excerpt

Using a high-copy-number suppressor screen to obtain clues about the role of the yeast RNA polymerase II subunit RPB4 in transcription, we identified three suppressors of the temperature sensitivity resulting from deletion of the RPB4 gene (DeltaRPB4). One suppressor is Sro9p, a protein related to La protein, another is the nucleosporin Nsp1p, and the third is the RNA polymerase II subunit RPB7. Suppression by...

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Identifiers

PMID: 11027282
DOI: 10.1128/MCB.20.21.8124-8133.2000
PMCID: PMC86422

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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Multiple mechanisms of suppression circumvent transcription defects in an RNA polymerase mutant.PMID 11027282Read ↗

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