Article
Immunological and functional analyses of the extracellular domain of human tissue factor.
Biological chemistry - 1 Feb 1998
Magdolen V, Albrecht S, Kotzsch M, Haller C, Bürgle M, Jacob U, Grosser M, Kessler H, Graeff H, Müller M, Schmitt M, Luther T
Abstract excerpt
Tissue factor (TF) initiates the extrinsic pathway of blood coagulation via formation of an enzymatic complex with coagulation factor VII/VIIa (FVII/VIIa). Although FVII is the only known ligand for TF, several reports in recent years have shown that the function of TF may not be limited to servi...
Topics
- Antibodies, Monoclonal
- Binding Sites
- Coagulants
- Epitope Mapping
- Epitopes, B-Lymphocyte
- Escherichia coli
- Gene Expression
- Genetic Variation
- Humans
- Recombinant Fusion Proteins
- Thromboplastin