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Article

Tissue Factor and Cancer

1 Jan 2007

Abstract excerpt

Tissue factor (TF), the key regulator of haemostasis and angiogenesis, is also involved in the pathology of several diseases, including cardiovascular, inflammatory and neoplastic conditions. In the latter, TF is upregulated by cancer cells, as well as by certain host cells, and it is the interactions between these distinct pools of TF-expressing cells that likely influence tumour progression in several ways....

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PMID: 19176989
DOI: 10.1159/000175154

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