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Article

Analysis of local structure in the D2/S1-S2 region of the rat skeletal muscle type 1 sodium channel using insertional mutagenesis.

Journal of neurochemistry - 1 Apr 1998

Kraner S D, Filatov G N, Sun W, Bannerman P, Lindstrom J, Barchi R L

Abstract excerpt

A reporter epitope was inserted at 11 positions in a region encompassing proposed transmembrane segments S1 and S2 in the second repeat domain (D2) of the rat skeletal muscle type 1 sodium channel. All mutations produced full-length membrane-associated protein following transfection into cultured cells, although the level of expression varied with insertion position. Characterization of cognate cRNAs for each...

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PMID: 9523580
DOI: 10.1046/j.1471-4159.1998.70041628.x

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

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