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Article

Structure-function studies of claudin extracellular domains by cysteine-scanning mutagenesis.

The Journal of biological chemistry - 16 Oct 2009

Angelow Susanne, Yu Alan S L

Abstract excerpt

Claudins form size- and charge-selective pores in the tight junction that control the paracellular flux of inorganic ions and small molecules. However, the structural basis for ion selectivity of paracellular pores is poorly understood. Here we applied cysteine scanning to map the paracellular pa...

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Identifiers

PMID: 19690347
DOI: 10.1074/jbc.M109.043752
PMCID: PMC2781464

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 2 Sept 2026. Prepared record publication-19690347-2026-09-02.2. Manifest publication-graph-cohort-2026-09-02.2.

Source receipt: PubMed via Helena Literature Corpus, retrieved 2 Sept 2026.

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