Article
Celiac disease and HLA-DQ genotype: diagnosis of different genetic risk profiles related to the age in Badajoz, southwestern Spain.
Revista espanola de enfermedades digestivas - 1 Sept 2013
Fernández-Cavada-Pollo María Jesús, Alcalá-Peña María Inmaculada, Vargas-Pérez María Luisa, Vergara-Prieto Esther, Vallcorba-Gómez-Del Valle Isabel, Melero-Ruiz Josefa, Márquez-Armenteros Ana María, Romero-Albillos José Alejandro, Narváez-Rodríguez Isidoro, Fernández-de-Mera José Juan, González-Roiz Cristina
Abstract excerpt
BACKGROUND AND OBJECTIVES: celiac disease is associated with the HLA class II alleles: DQA1*05-DQB1*02 and DQB1*0302. The genetic risk for celiac disease may depend on the presence or absence of such alleles, their combination or number of copies. This study aimed to establish the differences in HLA genotypes between celiac patients diagnosed during childhood and adulthood, and between patients and healthy...
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