Article
HLA-DQ distribution and risk assessment of celiac disease in a Spanish center.
Revista espanola de enfermedades digestivas - 1 Jul 2018
Martínez-Ojinaga Eva, Molina Manuel, Polanco Isabel, Urcelay Elena, Núñez Concepción
Abstract excerpt
AIMS: celiac disease is a multisystem immune-mediated disease triggered by gluten in genetically susceptible individuals. The HLA-DQ2 and/or HLA-DQ8 heterodimers are encoded by the main genetic predisposing factors and their presence is required for the development of the immunological response that leads to the disease. However, the HLA-conferred risk can differ within different countries. The aim of the study...
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